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Newer-Generation Ultrathin Strut Drug-Eluting Stents ...

Ultrathin, bioresorbable polymer sirolimus-eluting stents versus thin, durable polymer everolimus-eluting stents in patients undergoing coronary revascularisation (BIOFLOW V): a randomised trial. Lancet. 2017; 390:1843–1852. doi: 10.1016/S0140-6736(17)32249-3 Crossref Medline Google Scholar; 10. Higgins J, Green S. Cochrane Handbook for Systematic Reviews of Interventions The Cochrane ...

Newer-Generation Ultrathin Strut Drug-Eluting Stents ...

Background: Contemporary second-generation drug-eluting stents (DES) have superior efficacy and safety in comparison with early-generation stents in patients undergoing percutaneous coronary intervention, in part, related to their thinner struts. Whether newer-generation ultrathin DES further improve clinical outcomes in comparison with older second-generation thicker strut DES is unknown.

Ultrathin strut drug eluting stents for small vessel ...

Ultra thin strut drug eluting stents may an option in such cases. A study published in JAMA Cardiology compared ultra thin strut stents with very thin strut stents and previous generation drug eluting stents in small vessel coronary artery disease [1]. It was a pre-specified substudy of the Comparison of Biodegradable Polymer and Durable Polymer Drug-eluting Stents in an All Comers Population ...

Ultra-thin strut cobalt chromium bare metal stent usage in ...

The stent has an ultra-thin strut thickness down to 65 μm. Five different stent cellular configurations are used to span the five diameters of the full range, as illustrated in Fig. 1(stents range from 12 struts around the circumference for 2.5 mm stents to 20 struts around the circumference for 4 mm stents).

Ultrathin Bioresorbable-Polymer Sirolimus-Eluting Stents ...

Jensen LO, Maeng M, Raungaard B, et al. A randomized trial comparing a polymer-free coronary drug-eluting stent with an ultra-thin strut bioresorbable polymer-based drug-eluting stent in an allcomers patient population: SORT OUT IX. Presented at: TCT 2018; September 22, 2018; San Diego, CA. Google Scholar . 12. B.E. Claessen, M.A. Beijk, V. Legrand, et al.Two-year clinical, angiographic, and ...

Cobra Stent With Ultrathin Polymer Safe, Effective but ...

Among 287 patients treated with the Cobra coronary stent (CeloNova BioSciences), which is covered with a nanothin polymer designed to promote vessel healing, the rate of target vessel failure (TVF) at 9 months was 11.5%, a rate lower than that observed in a meta-analysis of BMS studies that served as the historical comparator. Among 115 patients who underwent angiographic follow-up, mean late ...

Ultrathin-Strut Orsiro Stent as Good as BioMatrix ...

The polylactic acid polymer on the stainless steel BioMatrix stent degrades in approximately 9 months while the poly-L-lactic polymer on the cobalt-chromium Orsiro stent degrades over 12 to 24 months. Additionally, Orsiro utilizes sirolimus as its antiproliferative drug, while BioMatrix uses biolimus A9.

TRACHEOBRONXANE™ DUMON® BB — Ultra Thin Stents | Novatech SA

DUMON ® BB stents are fully radiopaque (white) and have a wall thickness of only 0.5 mm. They are particularly suitable for small lumen airways. DUMON ® BB stents have very thin walls and only two rows of studs, facilitating introduction through the vocal cords.. The ratio between inner and outer diameter is very favorable, wall-thickness is only 0.5 mm. Stent placement is possible with ...

A third generation ultra-thin strut cobalt chromium stent ...

The present study was designed to evaluate a novel third generation bare-metal stent (BMS) comprised of an ultra-thin-strut, cobalt-chromium platform with fixed geometry, uniform cell size, and superior surface finish in a porcine coronary artery model.

Endoscopic ultrasound-guided choledochoduodenostomy ...

metal stent with a 5.9-Fr ultra-thin delivery system. ENDOSCOPY E-VIDEOS https://eref.thieme.de/e-videos Endoscopy E-Videos is a free access online section, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high quality video and all contributions are freely accessible online. This section has its own submission website at https://mc ...

Thin, Very Thin, or Ultrathin Strut Biodegradable or ...

Two such biodegradable polymer–coated DES are the ultrathin-strut Orsiro sirolimus-eluting stent (SES) (Biotronik, Bülach, Switzerland) and the very-thin-strut Synergy everolimus-eluting stent (EES) (Boston Scientific, Marlborough, Massachusetts).

BIOSCIENCE - Experimental coronary stent combines ...

BARCELONA, Spain – Monday 1 September: A new generation of coronary artery stent that combines a biodegradable component with an ultrathin scaffold showed promising results compared with the current gold standard, in a large population of coronary artery disease patients, according to a new study.

An Ultrathin Biodegradable Polymer Stent Is Superior for ...

Biodegradable polymers for everolimus drug elution combined with ultrathin-strut stents (BPEES) might mitigate inflammation and promote more rapid endothelialization than current third-generation, durable-polymer, sirolimus-eluting stents (DPSES).

Ultrathin-strut biodegradable polymer versus durable ...

These may be offset by real life challenges of the ultra-thin strut stent platforms including limited radiographic visibility and reduced radial stregnth and maximum diameter stent expansion limits. Conclusion. In this meta-analysis comparing modern generation DES platforms, patients randomly assigned to PCI with the ultrathin-strut biodegradable polymer stent (Orsiro) had reduced risk of ...

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Biodegradable polymer Evermine 50 everolimus eluting ...

biodegradable polymer, coronary artery disease, Everolimus, ultra-thin strut Significant development has been made in the field of percutaneous coronary intervention (PCI) from bare metal stents (BMS) to drugeluting stents (DES). The implantation of BMS was utilized as a minimally persistent treatment for disruptive CAD patients.

The ultra-thin strut sirolimus-eluting coronary stent ...

The SUPRAFLEX stent system has ultra-thin struts (60 μm) across all stent diameters and a biodegradable polymer coating, enabling 70% of the sirolimus elution within 7 days. SUPRAFLEX has been...

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Impact of ultra-thin struts on restenosis after chronic ...

Impact of ultra-thin struts on restenosis after chronic total occlusion recanalization: Insights from the randomized PRISON IV trial. Zivelonghi C(1)(2), Teeuwen K(3), Agostoni P(1), van der Schaaf RJ(4), Ribichini F(2), Adriaenssens T(5), Kelder JC(1), Tijssen JGP(6), Henriques JPS(6), Suttorp MJ(1). Author information: (1)Department of Cardiology, Sint Antonius Ziekenhuis, Nieuwegein, The ...

US6224626B1 - Ultra-thin expandable stent - Google Patents

Ultra-thin expandable stent Download PDF Info Publication number US6224626B1. US6224626B1 US09/283,800 US28380099A US6224626B1 US 6224626 B1 US6224626 B1 US 6224626B1 US 28380099 A US28380099 A US 28380099A US 6224626 B1 US6224626 B1 US 6224626B1 Authority US United States Prior art keywords stent ladder tubular rungs expandable stent Prior art date 1998-02-17 Legal status (The legal status is ...

BIOTRONIK’s Ultrathin Strut Orsiro Coronary Drug-Eluting ...

BIOTRONIK today announced three-year data from the BIOFLOW-V trial, which was presented yesterday at the 2020 CRT Congress. The three-year follow-up data demonstrates consistently lower clinical event rates and improvement in patient outcomes, reinforcing the differentiation of the Orsiro ® coronary drug-eluting stent (DES) – the first and only ultrathin strut DES to outperform Xience. 1, 2 ...

Ultrathin Struts Show Strength in Small Vessels: BIO ...

Implantation of the ultrathin-strut stents independently predicted a lower risk of TLR by 3 years (adjusted HR 0.42; 95%CI 0.20-0.85). There were no disparities among the three devices when it came to cardiac death, target-vessel MI, or stent thrombosis.

Ultra-thin metal Stent Accessories Mobile Phone Holder ...

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TCT Congress 2018: BIOTRONIK’s Orsiro Ultrathin Drug ...

1 Kandzari D, BIOFLOW-V: Two-Year Results of a Randomized Trial Evaluating an Ultra-thin Strut Bioresorbable Polymer-Based Drug-Eluting Stent. Presented at TCT, San Diego USA, September 2018 Presented at TCT, San Diego USA, September 2018

NOVATECH® GSS™ Y — Bifurcation Stents | Novatech SA

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Supraflex: A new ultra-thin drug releasing stent for ...

Supraflex is a new stent that has an ultra-thin wall and releases a drug called sirolimus. Xience is the standard stent used and releases a drug called everolimus. It is not known which of these stents has a better long-term outcome.

FDA Approves Orsiro Ultrathin-Strut Stent for CAD | tctmd.com

The stent will be available in 52 sizes, including diameters ranging from 2.25 to 4.0 mm and lengths up to 40 mm. The Orsiro stent, which has been marketed in Europe since 2011, is the only so-called ultrathin-strut device approved in the US. In 2017, the FDA approved the EluNIR ridaforolimus-eluting stent (Cardinal Health/Medinol) for the treatment of patients with coronary artery disease ...

FDA approves ultrathin bioabsorbable coronary stent

Biotronik announced that a drug-eluting stent system for the treatment of patients with CAD has been approved by the FDA and is commercially available in the U.S.The DES (Orsiro, Biotronik) is ...

SILMET® — Nitinol | Novatech SA

SILMET ® is a self-expanding stent made of nitinol, an alloy of nickel and titanium.. With nitinol, NOVATECH makes use of the shape-memory-effect which refers to the ability of nitinol to undergo shape deformation at one temperature, then recover its original undeformed shape at another temperature (here: body temperature).

Randomised comparison of a biodegradable polymer ultra ...

There was no definite or probable stent thrombosis in either group. Conclusions: In the treatment of de novo native coronary artery lesions, the biodegradable polymer ultra-thin SES (BioMime) was non-inferior to a durable polymer EES (XIENCE) at nine-month follow-up. Further studies powered for clinical endpoints are needed.

Three-Year Outcomes of Biodegradable Polymer-Coated Ultra ...

Three-Year Outcomes of Biodegradable Polymer-Coated Ultra-Thin (60 µm) Sirolimus-Eluting Stents in Real-World Clinical Practice Ann Acad Med Singap. 2019 May;48(5):150-155. Authors Prakash Chandwani 1 , Bhavesh Meel, Rahul Singhal, Kushal Jangid, Rasheed Ahmed, Mukesh Yadav, Anshul Kumar Gupta, Rohit Chopra. Affiliation 1 Department of ...

A randomised controlled trial of the sirolimus-eluting ...

A randomised controlled trial of the sirolimus-eluting biodegradable polymer ultra-thin Supraflex stent versus the everolimus-eluting biodegradable polymer SYNERGY stent for three-vessel coronary artery disease: rationale and design of the Multivessel TALENT trial . EuroIntervention 2020;16:e997-e1004. DOI: 10.4244/EIJ-D-20-00772. Hironori Hara 1, 2, MD; Chao Gao 2, 3, MD; Norihiro Kogame 1 ...

Safety and efficacy of a sirolimus-eluting coronary stent ...

Safety and efficacy of a sirolimus-eluting coronary stent with ultra-thin strut for treatment of atherosclerotic lesions (TALENT): a prospective multicentre randomised controlled trial Lancet. 2019 Mar 9;393(10175):987-997. doi: 10.1016/S0140-6736(18)32467-X. Epub 2019 Feb 28. Authors Azfar Zaman 1 , Robbert J de Winter 2 , Norihiro Kogame 3 , Chun Chin Chang 4 , Rodrigo Modolo 5 , Ernest ...

healthcare professionals Ultrathin StrutBioresorbable ...

The superiority of the Ultra-thin strut Orsiro stent is further strengthened by the recent data presented at the ACC meeting, showing that Orsiro outperforms all of the 3 contemporary durable polymer DES, namely: Xience, Resolute Integrity and Resolute Onyx. It is intriguing to postulate whether the impressive performance of the Orsiro stent is due to the unique bioresorbable polymer or due to ...

BIOTRONIK's Ultrathin Strut Orsiro Coronary Drug-Eluting ...

BIOTRONIK's Ultrathin Strut Orsiro Coronary Drug-Eluting Stent Continues to Deliver Excellent Results After Three Years Read full article February 24, 2020, 7:05 AM · 4 min read

Impact of kissing balloon in patients treated with ...

The ultrathin struts of new drug-eluting stents (DES) are associated with a lower risk of stent thrombosis (ST) and a lower rate of repeat revascularisation. However, there is a paucity of data regarding their safety and efficacy in left main lesions or coronary bifurcations.

Ultrathin strut Orsiro better than thin strut Xience for ...

The authors state: “The prespecified criterion for superiority of ultrathin strut biodegradable polymer sirolimus-eluting stents compared with thin strut durable polymer everolimus-eluting stents was met.” They add that this finding was “largely driven” by a lower rate of clinically-driven target revascularisation in the Orsiro group, noting that there were no differences in the rate ...

Multivessel TALENT - Full Text View - ClinicalTrials.gov

A randomised controlled trial of the sirolimus-eluting biodegradable polymer ultra-thin Supraflex stent versus the everolimus-eluting biodegradable polymer SYNERGY stent for three-vessel coronary artery disease: rationale and design of the Multivessel TALENT trial. EuroIntervention. 2020 Dec 18;16(12):e997-e1004. doi: 10.4244/EIJ-D-20-00772.

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FDA Approves BIOTRONIK's Ultrathin Orsiro Stent for the ...

2 Kandzari D et al. Ultrathin, bioresorbable polymer sirolimus-eluting stents versus thin, durable polymer everolimus-eluting stents in patients undergoing coronary revascularisation (BIOFLOW V ...

MonarchBio Continues to Build Substantial Thin-Film ...

An ultra-pure film of nitinol, 1-20 micrometers thick (for comparison, the average human hair is approximately 50 micrometers thick), is deposited on a silicon wafer with a specially designed ...

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